Step-by-Step Instructions

10. Point needle down and away

from yourself and others, and

push down on plunger to acti-

vate safety shield.

11. Place used syringe in sharps

collector.

7. With other hand, pinch an inch of

the cleansed area to make a fold

in skin. Insert full length of nee-

dle straight down — at a 90°

angle — into the fold of skin.

8. Press plunger with your thumb until

syringe is empty.

9. Pull needle straight out at the

same angle that it was inserted,

and release skin fold.

Please see additional Important Safety Information for

LOVENOX

on back.

Please see accompanying Full Prescribing Information

for Lovenox

, including boxed WARNING.

6. Hold syringe like a pencil in your

writing hand.

1. Wash and dry your hands

thoroughly.

5. Remove needle cap by pulling

it straight off the syringe and

discard in sharps collector.

2. Sit or lie in a comfortable

position, so that you can

see your abdomen.

3. Choose an area on the right or

left side of your abdomen, at

least 2 inches from your belly

button. Think “love handles.”

4. Clean the injection site with alcohol

swab. Let dry.

Step-by-Step Instructions

for self-injection

Important Safety Information for LOVENOX

(enoxaparin sodium injection)

You should call your doctor immediately if you notice any of the following: unusual bleeding or bleeding

that lasts a long time, unusual bruising, signs of thrombocytopenia (such as a rash or dark spots under the

skin), tingling or numbness (especially in the lower limbs), and muscular weakness.

Please visit

Lovenox.com

to view the patient injection video

Indication for LOVENOX

(enoxaparin sodium injection)

LOVENOX

can help reduce the risk of developing deep vein thrombosis (DVT) blood clots, which may lead to pulmonary embolism (PE), in

patients undergoing abdominal surgery, hip- or knee-replacement surgery, or in acutely ill medical patients with severely restricted mobility.

Important Safety Information for LOVENOX

If you are receiving epidural or spinal anesthesia or undergoing spinal puncture, and taking LOVENOX

(enoxaparin sodium injection),

you may be at increased risk of developing a blood clot in or around the spine, which can result in long-term paralysis. Your risk may be

further increased if you:

• Take nonsteroidal anti-inflammatory drugs (NSAIDs), platelet inhibitors, or other anticoagulants, such as aspirin or blood thinners

• Have an indwelling epidural catheter

• Have a history of spinal trauma, or repeated spinal anesthesia or punctures

• Have a history of spinal deformities or spinal surgery

It is important to contact your doctor immediately if you experience symptoms such as tingling, numbness (especially in the lower limbs),

or muscular weakness.

LOVENOX

should not be used in patients who are actively bleeding or who have a low count of blood cells called platelets, which aid

in clotting. This is a condition called “thrombocytopenia.” LOVENOX

also should not be used in patients who are allergic or sensitive to

LOVENOX

or enoxaparin, heparin, or pork products.

LOVENOX

must be used with care in patients who have any of the following: problems with clotting, uncontrolled high blood pressure, a

recent ulcer, impaired vision due to diabetes, kidney problems, and excessive bleeding. Pregnant women with mechanical prosthetic (artificial)

heart valves may be at higher risk for blood clots. These patients who are treated with LOVENOX

must be carefully monitored by their doctor.

Some patients on LOVENOX

can experience drops in their platelet counts, a condition called “thrombocytopenia.” Also, a serious but rare

condition called “heparin-induced thrombocytopenia” can occur with LOVENOX

. If you have had this condition, you must promptly notify

your healthcare professional.

LOVENOX

alters the blood’s ability to clot. Excessive bleeding (hemorrhage), leading to death, has occurred with LOVENOX

. Bleeding can

occur at any site with LOVENOX

use. The use of aspirin and other NSAIDs may enhance the risk of excessive bleeding. Be sure to tell all your

doctors and dentist about all of the medications you are taking, including those you are taking without a prescription, such as aspirin or other

NSAIDs. Also be sure to tell your doctor or dentist you are taking LOVENOX

before any surgery is scheduled and before any new drug is taken.

All patients should be carefully monitored by their doctor while taking LOVENOX

. Your doctor is likely to obtain blood tests that measure your

blood count and check for signs of hidden bleeding while you are on LOVENOX

You should call your doctor immediately if you notice any of the following: unusual bleeding or bleeding that lasts a long time, unusual

bruising, signs of thrombocytopenia (such as a rash or dark spots under the skin), tingling or numbness (especially in the lower limbs), and

muscular weakness.

The most common side effects from the use of LOVENOX

are mild pain, irritation, bruising, or redness of the skin at the site of injection.

Other common side effects include bleeding, anemia, diarrhea, nausea, ecchymosis, fever, edema, peripheral edema, dyspnea, confusion,

and injection site pain

Do not stop taking LOVENOX

without first talking to the doctor who prescribed it for you.

For specific questions about your health, you should always consult your doctor or a qualified healthcare professional who is responsible for

your care.

Please see accompanying full prescribing information for LOVENOX

, including boxed WARNING, for additional

important information.